Do antigen-binding molecules with weak affinity exist?

[Dims]

Do antigen-binding molecules with weak affinity exist and well-studied? Weak antibodies, weak receptors? Where I can read about them?

[CharonY]

Well "weak" is relative, of course. There are receptors and antibodies with different binding constants. For direct measurement of forces there are some AFM papers around, otherwise normally dissociation constants are sometimes given. I cannot easily point you to a certain group of paper in this regard. You'd have to be slightly more specific.