Adenovirus 12 infection vs. BLS

[smen]

What common features are involved in adenovirus 12 infection and bare-lymphocyte syndrome?

[jimmydasaint]

First of all, define your terms and do your own groundwork. For example what is bare lymphocyte syndrome? It looks like BLS is an autosomal recessive disease which involves severe combined immunodeficiency. Now ask yourself how Adenovirus 12 interacts with certain genes of the immune system by doing a quick search of scholarly articles. Then cross-reference and you will find an hypothesis. I see you have posted this terse enquiry on another Forum as well...

 

Anyway, being a kindly guy, I will give you a lead and you can follow up with a fuller explanation and teach the rest of us in return. Try to think of gene regulation of Major Histocompatability antigens (Class II and I)

 

http://www.authoratory.com/authors/2002/1087946749/1/pubs.htm

Edited August 9, 2008 by jimmydasaint
Addition of link and correction of minor error