White Cat Posted January 7, 2009 Share Posted January 7, 2009 Hi everyone i am new to this forum. I was hoping to get opinion on how people test for these resistance mechanisms in the first line and then what further testing the carry out to confirm. Also what experiences do people have of them Link to comment Share on other sites More sharing options...
Dotsie Posted January 7, 2009 Share Posted January 7, 2009 Hi White Cat The easiest way is to first check for cefpodoxime resistance, then use cefpodoxime/clavulanate disc diffusion (10 + 1ug discs) to check for synergy in all cef resistant isolates. If the cef/clav zone is 5mm or more larger than cef alone, the isolate is ESBL positive. This is the BSAC recommendation as well, which is the best thing to use if you are working in the UK Hope this helps. 1 Link to comment Share on other sites More sharing options...
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