blazinfury Posted April 7, 2009 Posted April 7, 2009 I need to synthesize, Phensuximide. The molecule is attached below. I need to begin with a benzaldehyde. Any advice? Thanks.
Kaeroll Posted April 7, 2009 Posted April 7, 2009 Found a decent (at first glance... I emphasise the brevity of my search here) looking paper on the synthesis of derivatives of your compound. The reference is Miller et al, J Am Chem Soc 1951, 73 (12), pp5608-5610. If you're looking for a retrosynthetic analysis I can't help you - I'm rustier than I care to admit with some of this chemistry.
UC Posted April 8, 2009 Posted April 8, 2009 (edited) Big hint: start with a wittig reaction to make styrene. SN2 will be important later on. Think cyanide. Edited April 8, 2009 by UC
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