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Now, if someone doesn't aprreciate music, you may be able to correctly state that there is something wrong with their brain; specifically the rostromedial prefrontal cortex. New research published in Science, this area of the brain is responsible for remembering music and recognizing tones, and also noticing bad notes when we hear a familiar tune.

To do this study, functional magnetic resonance imaging was used on subjects to identify areas of activity while listening to music, they were also asked to indentify timbral deviances in the songs. Increased activity in the middle temporal gyrus was also observed, and the right hemisphere was the most active.

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