Theophrastus Posted October 3, 2009 Posted October 3, 2009 What would be the products, in adding a strong base, like sodium hydroxide to acetaminophen? [ce] NaOH + HO-(C6H4)-NH-CO-CH3 -> [/ce]
John Cuthber Posted October 3, 2009 Posted October 3, 2009 Do you have any initial guesses that we might comment on?
UC Posted October 3, 2009 Posted October 3, 2009 What functional group is R-NH-C(=O)-R? It undergoes characteristic reactions with strong bases and acids. Google, grasshopper.
Theophrastus Posted October 3, 2009 Author Posted October 3, 2009 (edited) What functional group is R-NH-C(=O)-R? It undergoes characteristic reactions with strong bases and acids. Google' date=' grasshopper.[/quote'] Oh damn, no need to google this one. Yeah, now that you think of it that way (the non- idiotic way), I'm guessing my products ought be sodium acetate (What could I use that for I wonder ) and p-aminophenol, which could be rather useful. P- Aminophenol would be insoluble, in water (which would be my solvent of choice for the [ce] NaOH [/ce]) so I can remove that to use in various organic syntheses, and then of course, anyone whose played with hot ice knows that it's properties are just plain fun! Out of interest, are there any particularly interesting uses, whether as a reagent for organic synthesis or whatnot, for p- aminophenol? Edited October 3, 2009 by Theophrastus
Theophrastus Posted October 4, 2009 Author Posted October 4, 2009 (edited) Ah, forgot to take note of that, that'll mean I'll have "sodium oxyphenylamine", which upon the addition of acid, will give me p- aminophenol. Edited October 4, 2009 by Theophrastus
hermanntrude Posted October 4, 2009 Posted October 4, 2009 where did you get a supply of pure acetaminophen?
UC Posted October 4, 2009 Posted October 4, 2009 where did you get a supply of pure acetaminophen? Just a guess- Cheapo uncoated off-brand acetaminophen tablets are not hard to come by and it's relatively easy to recrystallize. The fillers and binders are only a small portion of the tablet weight and are generally insoluble in most solvents. Aspirin can be recrystallized in a similar manner, using hot acetone to extract the tablets. Slow evaporation gives large, transparent crystals in my experience.
hermanntrude Posted October 4, 2009 Posted October 4, 2009 nice. I didn't realise it'd be so easy to extract
Theophrastus Posted October 8, 2009 Author Posted October 8, 2009 (edited) Sorry for the late post... but yeah, UC got it right. I'm using tylenol, actually (not the vile suspension, but the tablets), which where I come from is easy to come by, and relatively cheap. Joy. Edited October 8, 2009 by Theophrastus Consecutive posts merged.
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