immunodominance

[kobi]

hi. I need data for immunodominant CTL epitopes.

there are several definitions for "immunodominance". some studies refer all epitope that induce response as immunodominant. however, more correct immunodominance definition is the competition in inducing response between several epitopes expressed on the same cell at the same time. this kind of data is very rare. do you have any idea? thanks/

[dttom]

So does it mean if you take a CTL from an individual in one species then transfer that CTL to another individual in another species (simply for the purpose of triggering immunoresponse, delivering it to another individual is also okay, though of course with difference), the induced Ig should bind to what you expect to be immunodominant epitope according to your second definition?

I suspect 'immunodominant epitope' should vary, for the reasons that different species should response quite differently towards the transfer, and different species or even individual in the same species would have different immunotolerance.