Idiopathic peripheral neuropathy

[Blakelyneal]

Okay, so does anybody have any ideas on how to combat the acceleration of this problem or how to rebuild the myelin sheath around the nerves?

 

currently it is classified as idiopathic although the doctors have eluded to it being a possible diabetic neuropathy, but they are not sure.

 

lets brainstorm.

 

Go.

Edited February 21, 2010 by Blakelyneal
misspelling and re-writing some

[jimmydasaint]

Lorenzo's Oil came immediately to mind

http://en.wikipedia.org/wiki/Lorenzo_Odone

and the Myelin Project

http://en.wikipedia.org/wiki/The_Myelin_Project

[Blakelyneal]

Well, although these two sources could possibly one day be helpful, there isn't much help for people who already have damage to the myelin sheathing as is the case with the an already occurring neuropathy.

 

But I do like the information, at least there are some groups working towards re-myelination.

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Maybe an increase somehow of Glial cells would have an impact on re-myelinating the nerves.

 

Ill grab some sources real quick

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Schwann cells are glial cells found to work in peripheral nervous systems, if these were to be increased in individuals that have a neuropathy it is a possibility that they may re-myelinate the demyelinated nerves.

 

Are there any studies going on to initiate an increase in these cells?

 

I will work on an answer to that later, now I need to study organic.

Night all,

Blakely Jones

 

 

http://blustein.tripod.com/Schwann_Cells/schwann_cells.htm

http://en.wikipedia.org/wiki/Schwann_cell

http://www.biology-online.org/dictionary/Schwann_cells

[jimmydasaint]

Dear Bleakeyneal,

 

I did a quick 'scholar' search and found that there are some chemicals which can encourage mouse nerve cells to re-myelinate. Tumor Necrosis Factor alpha is one of these. Problem is, this is in mice at the moment. The Schwann cell angle is good, however, remember that cells go through the cell cycle and divide in response to growth factors. These growth factors are a better bet for re-myelination rather than going for Schwann cells alone. Also check out the papers underneath the reference below.

 

http://www.jneurosci.org/cgi/content/short/23/30/9824

 

Best wishes mate

 

Jim