Thermodynamic Box

[fid786]

A myoglobin had the protonation of a histidine residue coupled to the oxidation of a heme. The histidine had a pKA of 6.0 when the heme is oxidized and 7.1 when the heme is reduced. At pH 9.5, the reduction potential of the heme is +275 mV vs NHE.

 

(a) Draw the thermodynamic box that describes this system

 

(b) Predict the reduction potential at pH 3.

[Phi for All]

I'm going to move this to Homework Help.

 

 

 

What have you got so far?

[fid786]

I could not do this problem. I was having problems understanding how to make the box.