Bonds Question

[pat]

"The major non-covalent forces related to the formation of protein structures are H-Bonds, ionic interactions(electrostatic interactions), and hydrophobic interactions(which are caused by things like Van der waals forces). Give (draw) examples of how the dipeptide (L-Asn-L-Leu) could participate in each one of those types of interactions with functional groups frequently found in proteins? Make it clear exactly what atom/group is interacting with what other atom/groups. Explain the interaction you have drawn and why they fit one of the three categories given? " --I know this is a mouthful but any help would be greatly appreciated!!

[Mr Skeptic]

Well consider the functional groups on these:

Asn:

 

Leu:

 

Be careful not to include the part of the molecule that would form the C-N backbone.

[Charlatan]

"The major non-covalent forces related to the formation of protein structures are H-Bonds, ionic interactions(electrostatic interactions), and hydrophobic interactions(which are caused by things like Van der waals forces). Give (draw) examples of how the dipeptide (L-Asn-L-Leu) could participate in each one of those types of interactions with functional groups frequently found in proteins? Make it clear exactly what atom/group is interacting with what other atom/groups. Explain the interaction you have drawn and why they fit one of the three categories given? " --I know this is a mouthful but any help would be greatly appreciated!!

 

Protiens are formed by [hydrogen cells], [electric cells] and [water resisting cells]. That makes [water] + [energy] + [dense cells] making a protien.

 

The surrounding cell will absorb the [water], absorb the [energy] and have no reactions with the [water resisting] cells doing nothing to the dipeptide as they do not 'gel' at all.

 

Now, my diagram...

 

[Hydrogen cells] [dense cells]--->stabilising peptide form

\ /

activity-->\ /<--------------no activity, physical bond

\ /

[energy cells]

v

Interacts with peptide outer layer

 

Great success! We done it and finnish!

[Mr Skeptic]

pat, we won't help unless you can show you did some work. What have you got so far?

 

Charlatan, pat specifically asked about not forming proteins (that's covalent).

[pat]

pat, we won't help unless you can show you did some work. What have you got so far?

 

Charlatan, pat specifically asked about not forming proteins (that's covalent).

 

Ok, so far, for the H-bonds, i'm showing Leu-C=0---H-O-Tyr of a another protein, which shows that Hydrogen is interacting with another electronegative element. I also have the ionic interaction finished in a similar fashion, but i am stuck on the hydrophobic interaction. Don't know how to show that..

[Mr Skeptic]

Well, hydrophobic things are non-polar. See any non-polar functional groups? Oh, and you might want to use the carbonyl on the Asn instead of on the Leu, since on the Asn it's definitely not part of the C-N backbone.