canidae Posted May 12, 2010 Posted May 12, 2010 Can somebody give me some recommendation how to create the input file for the genetic program Admix 2.0 (Dupanloup and Bertorelle 2001)? I have data from 10 microsatellites and my PC has a Windows system. Greetings, Canidae
CharonY Posted May 12, 2010 Posted May 12, 2010 The authors describe their input file on their homepage. You may want to look there.
canidae Posted May 13, 2010 Author Posted May 13, 2010 Thanks Charon, it was the first I did, but there I can’t understand the part “ In case of microsatellite data, the molecular distance is the squared difference in allele size (see Bertorelle & Excoffier for more details).” I find also Bertorelle & Excoffier paper, but in my opinion the authors describe very briefly the procedure and it is still unclear for me. Do you know any genetic program able to convert input file for Admix?
CharonY Posted May 13, 2010 Posted May 13, 2010 I am not sure where the problem is. It requires as an input the averaged difference in allele size squared. See also the reasoning here: SLATKIN, M. 1995. A measure of population subdivision based on microsatellite allele frequencies. Genetics 139: 457–462. I am not sure whether there is a tool out there doing all the formatting for you, though. Relatively few but popular tools get third-party add-ons.
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