nec209 Posted July 28, 2010 Posted July 28, 2010 (edited) So I 'm talking to this guy on MSN and this want he is saying .. drugs go to all cells and not just infected ones, thats the problem i see here about drugs, its bc of that that the whole body gets worse everyday and not better. and if the good cells detect thats somethings going worse, they will act leaving behind the cancer cells so they can continue procreating and infecting more and more... and YES there is a product that blinds the cells, it give strength to the good ones, so the cancer ones cant affect them, and if the cancer cells cant affect good cells they will begin losing territory, then cancer will begin to fade. it will keep on reproducing, but in a lower quantity. and if the good cells are getting stronger, they will be able to defeat the bad ones, also it blinds the cancer cells, so when it reproduces, the product will have twice as blind as the "mother" also the withe globules will help. finally the cancer will begin to die because it cant reproduce anymore. we all have since birth cancer cells but in such a low quantity thats named to be null. while we grow, what we eat and what we exposed to is what determines if that cells will begin to grow or not, and if yours have began to just treat yourself with a good nutrition, exercise and that stuff... but also with this marvelous product called monavie. Other guy he is saying cancer should have protein marker on it.So the drug companies should be able to make atibodie to bind to the receptor just like they make atibodie to bind to virus or bacteria. My quetion why do people oppose chemo or radiation? Has for drugs that can tell cells what to do that does not exit.Cancer and organs going bad is a cellular problem.No drug exit or the know how to manipulate anything at a cellular level. But was reading on new technology called proton radiation very effective and little side effects but way to cosly .Only 2 or 3 places in the US has it do to it is very costly.Other new technology nanowire that is put in the body over the cancer that gives out UV radiation or gets very hot.These are new technology and will not be available for long time. Other people are working on atibodie in the lab. What is your thought on this and what do we do? Related topic http://www.scienceforums.net/topic/50513-dna-repair-scissors-discovered/ Edited July 28, 2010 by nec209
CharonY Posted July 28, 2010 Posted July 28, 2010 (edited) The quotes you posted have quite a bit of misinformation in it. Cancer cells are for the most part normal cells that mutated for a reason or another (including virus infections) that resulted in a deregulation of their proliferation. Thus the assumption that you already start out with cancer cells is half-wrong. They eventually become cancer cells. The second quote is also wrong as it simply would not work. Cancer cells are your normal body cells, but are deregulated. That means that all the surface proteins it carries will be found in a couple of other cell types, too. What is different is will be the amount of the proteins, which is why they can be biomarkers (though most are not very good diagnostic tools). Edited July 29, 2010 by CharonY
Mr Skeptic Posted July 29, 2010 Posted July 29, 2010 Cancer cells are your own cells gone rogue. This is going to have to be due to some sort of mutation. A successful cancer is going to need two mutation types: one to disable restrictions on cell reproduction, and a second to eliminate cell aging. Cancer cells are for the most part indistinguishable from healthy cells, and also are unique to each individual. There are some differences, the most notable one is that they reproduce faster. Thus, killing fast-reproducing cells will preferentially kill cancer cells -- but also your hair, sperm, etc. cells and make you feel very very sick (which you will be with all those cells dying) -- and this is the purpose of chemo and radiation treatments. A bonus of radiation treatments is that they can be focused so that the cancer part gets far more radiation than the rest of your body -- but it will still kill plenty of healthy cells.
CharonY Posted July 29, 2010 Posted July 29, 2010 (edited) Actually the mechanical, physicochemical and also often morphological properties are often quite different (and not only proliferation rate). For instance, cancer cells can become motile, requiring a massive reorganization in the cytoskeleton. Edited July 29, 2010 by CharonY
Moontanman Posted July 29, 2010 Posted July 29, 2010 I think it should be pointed out that not only is each persons cancer unique all types of cancer are different as well. there will probably never be a one time cure for cancer across the board for much the same reason that different other diseases are not cured by the same thing, Cancer is many different diseases that share similarities but are still different, much like the need for different antibiotics for different bacteria different cancers require different cures.... Then there is the immune system, the reality is that cancer cells develop all the time in all of us but our immune systems recognize them and kill them, only when a cancer gets around this does it proliferate and kill us. Sometimes our immune system "wakes up" and even end stage cancer can be eliminated by the body, hence miraculous cures.... yeah, I've been asking questions when i go to the doctor
nec209 Posted July 29, 2010 Author Posted July 29, 2010 The second quote is also wrong as it simply would not work. Cancer cells are your normal body cells, but are deregulated. That means that all the surface proteins it carries will be found in a couple of other cell types, too. What is different is will be the amount of the proteins, which is why they can be biomarkers (though most are not very good diagnostic tools). What do you mean? Can you or some one here explain this better to me.
CharonY Posted July 29, 2010 Posted July 29, 2010 (edited) The problem with throwing antibodies on it is the following. Genetically the cancer cells are identical to normal cells, except for the mutations. Antibodies, however, act by binding to antigens, in this case surface proteins of the cancer cells. Since the proteins are identical to other cells in your body, the antibodies will also bind to those cells. The affinity to cancer cells may be stronger, but you cannot simply flood the body with antibodies as it will result in adverse reactions to your healthy cells, too. A bit akin to autoimmune responses, maybe. That is why you cannot vaccinate against cancer cells, they are basically still your own cells (you can vaccinate against viruses that may cause certain types of cancers, though) Edited July 29, 2010 by CharonY
Mr Skeptic Posted July 29, 2010 Posted July 29, 2010 Actually the mechanical, physicochemical and also often morphological properties are often quite different (and not only proliferation rate). For instance, cancer cells can become motile, requiring a massive reorganization in the cytoskeleton. Right, and there's even been several attempts to use these other differences for a cure. Not nearly as easy as if they had unique proteins that could be targeted though. Even though the differences could be enough for a human to tell them apart at first glance, that doesn't really help from a biochemical cure perspective.
CharonY Posted July 29, 2010 Posted July 29, 2010 Well, there are biochemical differences in terms of activity (including, but not limited to cell proliferation, cell motility and so on). But as the cells are part of the body (rather than external agents) there will be no qualitative differences in composition, but only quantitative.
nec209 Posted July 29, 2010 Author Posted July 29, 2010 The problem with throwing antibodies on it is the following. Genetically the cancer cells are identical to normal cells, except for the mutations. Antibodies, however, act by binding to antigens, in this case surface proteins of the cancer cells. Since the proteins are identical to other cells in your body, the antibodies will also bind to those cells. The affinity to cancer cells may be stronger, but you cannot simply flood the body with antibodies as it will result in adverse reactions to your healthy cells, too. A bit akin to autoimmune responses, maybe. That is why you cannot vaccinate against cancer cells, they are basically still your own cells (you can vaccinate against viruses that may cause certain types of cancers, though) So cancer cells have the same protein marker has normal cells that is why vaccine or antibodies will not work !!Any antibody will go after cancer cells and normal cells has they have the same protein marker. So how does chemo or radiation work than ? What are the drug companies going to do?
Mr Skeptic Posted July 30, 2010 Posted July 30, 2010 As CharonY said, there are some qualitative differences. The most targettable one seems to be their rapid reproduction -- reproduction is a complex process with many requirements and many things that can go wrong, so it is a good target. This is why the common casualty of cancer treatment is loss of hair, since hair also reproduces rapidly.
nec209 Posted July 30, 2010 Author Posted July 30, 2010 As CharonY said, there are some qualitative differences. The most targettable one seems to be their rapid reproduction -- reproduction is a complex process with many requirements and many things that can go wrong, so it is a good target. This is why the common casualty of cancer treatment is loss of hair, since hair also reproduces rapidly. I did not see that post .Where is it? Where was he explaining that.
nec209 Posted August 11, 2010 Author Posted August 11, 2010 sorry I should have rephrase my question. cancer cells have the same protein marker has normal cells !!So how can they make drugs to go after the cancer cells if it has the same protein marker.
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