bluelantern Posted December 1, 2010 Share Posted December 1, 2010 So I know I said that I only had one question, but it looks like I have another one. The question on my assignment is as follows: A medical technologist became very confused at the result of a CBC she completed on a patient. As she went to pick up the tube off of the mixer, she noticed a large number of very small clumps in the tube. After she put the tube in a beaker of warm water (37o C), the clumps disappeared. She re-ran the CBC and the results looked more like the results of a patient who was actually alive. What could have caused this clumping? I'm really not sure what this clumping could be. I'm torn between 2 answers here. The first: the clumping is the result of platelets clotting. The second: This patient probably has multiple myeloma or hepatitis C. I believe this to be the answer I'm after due to the presence of cryoglobulins. These would "un-clump" if placed in the 37 degree water right? I'm not very familiar with a CBC test though and I could be off base. Any help is much appreciated and thanks in advance!! Link to comment Share on other sites More sharing options...
Twinbird24 Posted December 1, 2010 Share Posted December 1, 2010 (edited) Could also be this (Cold agglutinin disease): Cold agglutinins are autoantibodies that cause red blood cells to clump, but only when the blood is cooled below the normal body temperature of 98.6°F (37°C). The clumping is most pronounced at temperatures below 78°F (25.6°C). http://medical-dictionary.thefreedictionary.com/cold+agglutinins+test I don't think it is platelets clotting. Edited December 1, 2010 by Twinbird24 Link to comment Share on other sites More sharing options...
bluelantern Posted December 2, 2010 Author Share Posted December 2, 2010 Could also be this (Cold agglutinin disease): s Cold agglutinins are autoantibodies that cause red blood cells to clump, but only when the blood is cooled below the normal body temperature of 98.6°F (37°C). The clumping is most pronounced at temperatures below 78°F (25.6°C). http://medical-dicti...gglutinins+test I don't think it is platelets clotting. Holy hell this is exactly what the answer is. I completely forgot about these antibodies! You just earned me an extra 5% on my final exam. Pour yourself a drink! Link to comment Share on other sites More sharing options...
Twinbird24 Posted December 2, 2010 Share Posted December 2, 2010 yay! Link to comment Share on other sites More sharing options...
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