ohoneo Posted October 24, 2011 Posted October 24, 2011 Hi all, I hope this is the right forum. I'm currently in a biochemistry class in my college and while I'm enjoying it, I'm finding that some of the practice problems prove rather difficult. Especially because it's so hard to find additional help on the Internet for them! I'm stuck on a problem, that I've copied and pasted below, along with my attempt to solve it: A primary structure of tRNA(Val) is pGGU UUC GUm1G GUC (psi)AG DGG DDA UGG CA(psi) CUG C(psi)U IAC ACG CAG AAC m7GDC m5CCC AGT (psi)CG m1AUC CUG GGC GAA AUC ACC A . Draw the secondary structure of tRNA indicate acceptor stem, D loop, T(psi)C loop, anticodon loop, variable loop, and CCA terminus. Draw the full chemical structures of the nucleotides m1G, m7G, m5C, I, psi, D. My attempt: tRNA I know I haven't drawn the full chemical structures, that's not my issue (not yet anyway!) My issue is that I'm really not sure about what I'm doing, and there's nothing in my textbook to help me, other than saying that tRNA has an acceptor stem, D, loop, T(psi)C loop, anticodon loop, variable loop, and CCA tail and how many nucleotides are in those sections. When drawing the secondary structure, I drew the nucleotides from left to right (starting with the acceptor stem, and then going left to the D arm). However, I had nucleotides from the primary structure left over, and I wasn't even sure if I was proceeding in the right direction. Also, I wasn't entirely sure if the modifications's subscripts referred to a specific modification or the location of it. Any help is much appreciated!
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