Negishi Coupling

[organicsurfer]

Does anyone know if it is possible for a molecule of a secondary dibromoalkyl, Br-R¹-Br ( eg R¹ = 1,4-dibromo cyclohexane) to undergo conventional Negishi coupling with two molecules ( or slightexcess ) of a bromozinc alkylester, BrZn-R²( eg R² = BrZnCH₂COO.C₂H₅) to give R²- R¹ –R² ?

 

Will BOTH the Br in Br-R¹-Brreact together equally at the same rate ? If yes, and if there is a Journalreference mentioning dibromo couplings,similar to above, then kindly quotethis.

 

All the Journal literatures and study is only about monobromocompounds ( Br – R ). No one has researched or mentioned about dibromo compoundcouplings. Your input will be appreciated,thanks.