Guest Monkey3445 Posted November 22, 2004 Posted November 22, 2004 So if you know, or know how to find out, plz share.
Drug addict Posted November 22, 2004 Posted November 22, 2004 should be in a pharmacopeia (British, US or European), or in the Merck manual.
Gilded Posted November 23, 2004 Posted November 23, 2004 Rather odd, I can't seem to find it anywhere. It appears to be a mixture of dimethyl polysiloxanes, but that's where my knowledge about simethicone ends. :|
m/z Posted November 23, 2004 Posted November 23, 2004 "The anti-foaming agent Simethicone is a complex mixture of high molecular weight polydimethylsiloxane (PDMS) oligomers (approximately 92%) with particulate silicon dioxide added to enhance the defoaming properties of the silicone oil. The PDMS is characterised in terms of its viscosity of about 60 000 centiStokes, corresponding to an average molecular weight of about 27 000 Daltons." from Moore, Douglas E.; Liu, Tina X.; Miao, William G.; Edwards, Alison; Elliss, Russell. A RP-LC method with evaporative light scattering detection for the assay of simethicone in pharmaceutical formulations. Journal of Pharmaceutical and Biomedical Analysis (2002), 30(2), 273-278. Regards, m/z
apathy Posted November 24, 2004 Posted November 24, 2004 structure of poly[dimethylsiloxane] Just in case anyone cared.
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