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Chem Project, I need the chemical structure of simethicone


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Guest Monkey3445
Posted

So if you know, or know how to find out, plz share.

Posted

Rather odd, I can't seem to find it anywhere. It appears to be a mixture of dimethyl polysiloxanes, but that's where my knowledge about simethicone ends. :|

Posted

"The anti-foaming agent Simethicone is a complex mixture of high molecular weight polydimethylsiloxane (PDMS) oligomers (approximately 92%) with particulate silicon dioxide added to enhance the defoaming properties of the silicone oil. The PDMS is characterised in terms of its viscosity of about 60 000 centiStokes, corresponding to an average molecular weight of about 27 000 Daltons."

 

from

Moore, Douglas E.; Liu, Tina X.; Miao, William G.; Edwards, Alison; Elliss, Russell. A RP-LC method with evaporative light scattering detection for the assay of simethicone in pharmaceutical formulations. Journal of Pharmaceutical and Biomedical Analysis (2002), 30(2), 273-278.

 

Regards,

m/z

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