rokudo Posted February 13, 2013 Posted February 13, 2013 Hey guys I am hoping that someone here who has a strong organic background can help me out. Quant, phys chem, no problems ... i got some question on the procedure for synthesis of 1-phenylethanol1) In the synthesis of 1-phenylethanol, we poured acetophenone into methanol. Next, we prep a solution of methanol, sodium methoxide, and sodium borohydride (in that order). so why we need to used sodium methoxide?? is it bcz its a strong nucleophilic and base for substitation ??2) why we need to used vacuum distillaton for purification of 1-phenylethanol, not the normal distillation... Thanks!
maverickruler Posted February 15, 2013 Posted February 15, 2013 1) u r right. to confirme look at the Fredel Craft alkylation and acylation... u will get ur answer.
John Cuthber Posted February 15, 2013 Posted February 15, 2013 (edited) 1) u r right. to confirme look at the Fredel Craft alkylation and acylation... u will get ur answer. No. Completely wrong. Rokudo, did you use lots of methoxide? Edited February 15, 2013 by John Cuthber
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