heliodromus Posted April 17, 2013 Share Posted April 17, 2013 Hello folks, I am currently working on a Simulation of the diffusion of Synapsin within the presynaptic terminal. My current problem lies in the dependencyfactor. I am using a System of PDEs. Does anyone have empirical information on the binding rates of Syn 1 toSVs and actin filaments? I try to make my model as realistic aspossible (using FEA and Multigrid Methods). I thought of a sort of"Beta-Function" describing the Binding-Behavior ofSynaspin. WhatI found was an old article on the saturation of Synapsin 1stating that there might be a saturation at 76 +- 40 µg Syn I per ngVesicle. There is no indication on how the behavior changes when anAP arrives. I am kind of new to this, I used to study computer science, so I wouldbe very grateful if someone could help me out. Sincerely yours Heliodromus Link to comment Share on other sites More sharing options...
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