heliodromus Posted April 17, 2013 Posted April 17, 2013 Hello folks, I am currently working on a Simulation of the diffusion of Synapsin within the presynaptic terminal. My current problem lies in the dependencyfactor. I am using a System of PDEs. Does anyone have empirical information on the binding rates of Syn 1 toSVs and actin filaments? I try to make my model as realistic aspossible (using FEA and Multigrid Methods). I thought of a sort of"Beta-Function" describing the Binding-Behavior ofSynaspin. WhatI found was an old article on the saturation of Synapsin 1stating that there might be a saturation at 76 +- 40 µg Syn I per ngVesicle. There is no indication on how the behavior changes when anAP arrives. I am kind of new to this, I used to study computer science, so I wouldbe very grateful if someone could help me out. Sincerely yours Heliodromus
Recommended Posts
Create an account or sign in to comment
You need to be a member in order to leave a comment
Create an account
Sign up for a new account in our community. It's easy!
Register a new accountSign in
Already have an account? Sign in here.
Sign In Now