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Blood agglutination..........


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Posted

Say a patient in a hospital was getting some blood put in her and her chart said she was type B. A donor was taken which was labeled type B, but just for safety they took a sample of both blood and mixed them, Agglutination occured. Now how could you find out which label is wrong considering you have type A, type O and type AB blood at your disposal but no Type B. Would type B be a control variable in this sort of expirement or...is there even a control.

 

Thx alot

Posted

Type A blood has type A antigens on the red bllod cells and anti-B antibodies in the plasma.

Type B has anti-A antigens.

Type AB has both A & B antigens, but no anti-A or anti-B antibodies.

Type O has no antigens, but has anti-A and anti-B antibodies.

 

Type A RBCs would aglutinate with type B or type O plasma. Type B RBCs would aglutinate with type A or type O plasma. Type AB RBCs would aglutinate with any other blood type plasma, while type O RBCs would not algutinate with any type plasma (hence type O being called the universal donor.)

 

So, you would need to separate the blood into RBCs and plasma and then see what happens when you start adding things together.

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