The Chemical Makeup of Blood Plasma

[Cutler.Phillippe]

Could anybody please tell me the chemical makeup of blood plasma? I already know about the different parts of blood, such as red blood cells, platelets, white blood cells, etc.

 

I'm simply asking for the chemicals/substances that are the basics parts of blood plasma so that i could possibly synthesize it for an experiment I'm testing. (Real blood will not work for it)

[BabcockHall]

There are certain proteins found in plasma. One class of them is the immunoglobulins, especially IgG. There are also proteins such as serum albumin and fatty acid binding proteins.

[John Cuthber]

It's mainly salty water, but in detail, it's incredibly complicated so the idea that you can synthesise it may prove very optimistic.

What are you trying to do?

[CharonY]

The largest amount protein in plasma (or blood in general) is albumin, which constitutes over half of the protein content (roughly 60%, though can be more depending on extraction method and measurement procedure) . Together with around 10-20 further blood proteins such as apolipoproteins, transferrin, fibrinogen, complement proteins, immunoglobulins they constitute about 95-97% of the total protein in blood.

 

The salt composition is relatively simple in comparison and as John already mentioned, it would really depend on the use of the artificial blood. Whether it should functionally resemble plasma, or has retention qualities similar to it (e.g. for spike and extraction analyses). The latter would depend a lot on the type of compound under investigation, for example.

Edited August 20, 2013 by CharonY

[Cutler.Phillippe]

Thanks! You told me exactly what i needed to know.