Ankit Gupta Posted October 3, 2013 Posted October 3, 2013 why do salt cause so much burn when it get mixed with blood on any wound ? or simply why it creates an intense burning effect on an open wound ?
Moontanman Posted October 3, 2013 Posted October 3, 2013 This is just a guess but i would think the ionic shock to the nerve cells causes the pain... 1
Strange Posted October 3, 2013 Posted October 3, 2013 And maybe osmosis causing cells to rupture releasing chemicals that stimulate the pain nerves. (Or something. IANAB )
Phi for All Posted October 3, 2013 Posted October 3, 2013 If you increase the salt level in a solution, doesn't that cause it to expand, become hypertonic? Might that swelling cause the pain? Notice that I'm asking and NOT telling. This seems more like chemistry than biology. Let me know if you want me to move it there.
CharonY Posted October 3, 2013 Posted October 3, 2013 I think this is close to the likely mechanism. However, I would assume that not any swelling is the responsible but the cell damage that a highly hypertonic solution may cause. Nerve signalling tend to get sensitized upon tissue damage (i.e. the wound) and I would speculate that the presence of salt or other harmful compounds would exacerbate this. In addition electrolyte sensing receptors may add to the overall response, i.e. further stimulating nociceptors.
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