Biochemistry Clinical Case Help

[AppleSNAP]

A patient with type 1 diabetes mellitus is admitted to the hospital after collapsing during 50 mile cycle race which he had entered to raise money for the charity. His blood glucose concentration is 25ml/dl. He is given 50% dextrose IV and makes rapid recovery. Plasma CK activity was normal on admission but 12 hrs later is reported as 280Ul/L. A urine sample taken on admission is positive for glucose and protein. Which of the following is/are true? Comment each sentence.

A. a very low HbA level would be expected

B. Exercise is known to decrease insulin requirements.

C. Since he was hypoglycemic on admission, the positive test for glucose in urine at the time must be an error.

D. The creatine kinase could be a direct result of exercise.

E. The protein urea indicated that he has diabetic nephropathy.

 

Gamma glutamyl transferase (GGT):

A, It uses glutathione as a substrate

B. It is the main liver enzyme useful for the diagnosis of hepatitis

C. It's increase in billiar/obstruction is associated with an elevation of alkaline phosphatase.

D. It is an inducible enzyme

E. It is markedly elevated in cases of chronic alcohol consumption.

Which sentences are correct? Comment on your choice.

 

C reactive protein

A. Is produced by monocytes stimulated by high LDL-cholesterol plasma level

B. High CRP plasma levels can predict coronary events in patients with stable or unstable angina.

C. Its synthesis is regulated by IL6

D. Its plasma value is not affected by inflammation

E. It is a marker of plaque rupture.

Which sentences are correct? Comment on your choice.

Edited January 12, 2014 by AppleSNAP

[imatfaal]

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