Does toothpaste chemicals may be damage to our health?

[chemicalman]

Note: My english isnt well.
Everyone knows toothpaste's has chemicals in variety. Floride is the main chemical. But how do you know if its not harm your health in the future?
May be it cause cancer in the future. So what precautions do you take when you brush your teeths?
How long have you brush your teeths?
Are you take mouthwash while you doing this?
Does toothpaste chemicals harm to human body?

[John Cuthber]

people have used toothpaste for many years.

If it harmed people we would have noticed.