blazinfury Posted September 17, 2014 Posted September 17, 2014 When a virus infects a cell it undergoes recombination with cell genome. I understand how recombination happens. So in the process, is a gene from virus delivered into human genome or human genome into viral genome or both can happen? I know that SRC is often transduced into the virus. Does that mean when a SRC virus enters a cell, the virus uses host machinery to rapidly proliferate and so in the process, the SRC, which is located after the 3 viral genes gag, pol, env, gets transcribed and translated using the viral LTR? Now I am confused how that leads to cancer. Is it that there is excessive proliferation of SRC and so what once was a proto-oncogene now has no control and becomes an oncogene?
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