How can human stem cell pass through intestinal walls

[victor43]

Hello.

Would anyone share what means could a human stem cell pass through the intestinal walls of our bowels and find their way into the blood steam ? I understand that this may not be possible as I have been told that stem cells are too big to pass through the intestinal walls however oligo elements such as the following (ions, sugars, amino acids, lipids) can pass through. Are these molecular elements larger in size than stem cells ? What I would like to know is how could it be possible not whether it can be achieved or not.

 

Thanks

[CharonY]

Eh, stem cells are cells. They are as large as other cells. How would a cell pass through a wall of intestinal cells (you are aware that our bowels are lined/formed by cells)?

Also cells contain lots of molecules, so they are always larger than them.

[Endy0816]

There's only the case of mixing when the wall itself is damaged(bad very bad).

 

Why the question? Some clarification could help.

[victor43]

There's only the case of mixing when the wall itself is damaged(bad very bad).

 

Why the question? Some clarification could help.

 

Thank you both of you for the responses. This question is simply theoretical in nature nothing else really. Can you tell me one thing though. Could some kind of organism (virus or parasite or bacteria) damage one or more cells of the intestinal tract allowing stem cells or any type human cell to pass through ? Is this plausible ?

[OptimisticCynic]

White blood cells move through tissue frequently. It is not like the intestinal wall is a solid structure. There is much flexibility to the cell walls and the material binding the cells together is not stiff like dry mortar in a brick wall.

I seem to recall reading something about stem cells moving through tissues on their own during certain stages of fetal growth?

[CharonY]

Yes they do and to some degree during tissue regeneration also in adults. I think OP is confusing cell membranes with tissue. Also, stem cells are more likely to end up in lumen leaking out from blood rather than vice versa.

[victor43]

White blood cells move through tissue frequently. It is not like the intestinal wall is a solid structure. There is much flexibility to the cell walls and the material binding the cells together is not stiff like dry mortar in a brick wall.

I seem to recall reading something about stem cells moving through tissues on their own during certain stages of fetal growth?

 

Hello. Thank you for the response. You had mentioned that stem cells were able to move through tissue correct ? Could you please provide any resources on this detail ? Tissue you mean like liver tissue, lung tissue, heart tissue yes ? Would tissue be considered to be just cells ? So you have said that stem cells could move through tissue meaning cells of the liver or cells of the appendix and etc ?

 

Thanks to Charon also.

[OptimisticCynic]

On Wikipedia, the article, "Leukocyte extravasation" is a starting point.