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what are the chances of getting diabetes with diabetic (type 2) grandma and mother ?


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Posted

I think diabetes is very heritable. My grandma has type 2 diabetes at her 60s, and now my mother finds out she has it too ! My grandfather has no problem with his blood sugar level at all, so does my father.

 

is it due to my mother's genetic reason that no matter how careful she deals with her food she still has diabetes ? if that is true, i will probably get it in future.

what are the chances of me getting diabetes ?

is it preventable ?

thanks.

 

Posted

There is a component of genetic predisposition, but much more relevant with type 2 diabetes are your diet and activity levels.

Posted (edited)

My grandmother and grandfather was never diagnosed with type 2 diabetes and they lived till their 80s. My auntie on the other hand found she had type 2 diabetes in her early 20s. My father never was diagnosed with diabetes but he had other problems. My sister was diagnosed with type 2 diabetes in her early 20s. Diabetes never featured in my mom's side of the family. My brother has never been diagnosed with type 2 diabetes and neither have I.

 

I think diabetes is very heritable. My grandma has type 2 diabetes at her 60s, and now my mother finds out she has it too ! My grandfather has no problem with his blood sugar level at all, so does my father.

 

Personally I wouldn't rule it being genetic out. Which just means that you really should be extra careful with your sugar intake etc. It doesn't hurt to test yourself every once in a while either. That's what I do never had an abnormal reading yet. But if it were genetic it is probably on a female gene that i couldn't have inherited from my dad.

Edited by fiveworlds
Posted

There is a component of genetic predisposition, but much more relevant with type 2 diabetes are your diet and activity levels.

 

my grandfather and father both love sweet food and food which rapidly raise your blood sugar level, fortunately they never worry about their blood sugar level at all, so i believe this disease has nothing to do with our diet but only to do with our gene.

why diabetes is probably on a female gene ?

From what i observe, people with high blood pressure will most probably get diabetes around 7-10 years later.

I have no idea why.

Posted (edited)

my grandfather and father both love sweet food and food which rapidly raise your blood sugar level, fortunately they never worry about their blood sugar level at all, so i believe this disease has nothing to do with our diet but only to do with our gene.

Well, you can continue believing that if you want, but then you'd be wrong: http://www.mayoclinic.org/diseases-conditions/type-2-diabetes/basics/risk-factors/con-20031902 Edited by iNow
Posted

 

why diabetes is probably on a female gene ?

 

 

That is just a theory about my own family since the two people who have diabetes in my family (aunt and sister) are both girls whereas the boys never had diabetes.

Posted

 

That is just a theory about my own family since the two people who have diabetes in my family (aunt and sister) are both girls whereas the boys never had diabetes.

 

it is so strange. i wanna know the scientific reasons behind it.

Posted (edited)

Well, you can continue believing that if you want, but then you'd be wrong: http://www.mayoclinic.org/diseases-conditions/type-2-diabetes/basics/risk-factors/con-20031902

 

thank you iNow, is it a way to prevent from getting diabetes ?

or the chances of getting diabetes with female diabetic relatives is almost 100% no matter how hard you try to prevent it ?

it is only matter of time...

Edited by fresh
Posted

 

thank you iNow, is it a way to prevent from getting diabetes ?

or the chances of getting diabetes with female diabetic relatives is almost 100% no matter how hard you try to prevent it ?

it is only matter of time...

inow has already answered this question in post #2. "There is a component of genetic predisposition, but much more relevant with type 2 diabetes are your diet and activity levels."

 

In other words, eat wisely and exercise regularily, ensuring that your are not overweight. This will not prevent you getting diabetes, but will greatly reduce the risk.

Posted

It's how you live with what you've got that matters most.

 

it doesn't apply to my mum & dad ......

my mum tries to avoid the food diabetics shouldn't eat as much as possible but gets diabetes whereas my dad eats whatever he likes and is diabetes free.

my dad is overweight while my mum is fit.

Posted

I shall keep repeating this, until there is some evidence that it has sunk in.

 

In other words, eat wisely and exercise regularily, ensuring that your are not overweight. This will not prevent you getting diabetes, but will greatly reduce the risk.

Posted

I shall keep repeating this, until there is some evidence that it has sunk in.

 

In other words, eat wisely and exercise regularily, ensuring that your are not overweight. This will not prevent you getting diabetes, but will greatly reduce the risk.

 

In general I do agree with you, Ophiolite, that lifestyle, diet, lack of exercise and obesity levels have greatest impact on Type 2 diabetes incidence rates, but there have been quite a few studies on genetical predisposition to getting it. For example:

 

http://www.nature.com/ng/journal/v38/n3/abs/ng1732.html

http://www.sciencedirect.com/science/article/pii/014067369291958B

http://link.springer.com/article/10.1007/s00125-007-0827-5

 

But also, drinking a lot of sweet beverages, not exercising and watching Oprah are also really bad:

 

http://jama.jamanetwork.com/article.aspx?articleid=196345&resultclick=1

Posted

As far as I know type 1 diabetes is more considered a genetically inherited disease, perhaps through an autoimmune process that kills off the pancreatic beta islets.

 

Type 2 diabetes may be more considered as a polygenic disease, as such the inheritance pattern may be more difficult to predict. A major component of type 2 insulin resistance is lifestyle, so lifestyle choices such as diet and exercise also factor into developing type 2 diabetes in a big way. Metabolic syndrome, waist circumference, glucose intolerance are things we can control, so it may be worth considering that it may be it is the lifestyle behaviour that is being passed on, as well as the genes in type 2 diabetes.

Posted

what the food and drink we take can lower the risk of getting diabetes ?

Generally, and this is not nessisarily in relation to diabetes, avoid too much processed sugar. Go for sugar free drinks and no sugar in your tea coffee. Avoid sugary sweets in between meals. Also eat a balanced diet, not too much fat and not too many carbohydrates.

Posted

 

That is just a theory about my own family since the two people who have diabetes in my family (aunt and sister) are both girls whereas the boys never had diabetes.

 

I don't think a sample size of 2 is enough to draw statistically significant conclusions.

 

it is so strange. i wanna know the scientific reasons behind it.

 

Coincidence.

Generally, and this is not nessisarily in relation to diabetes, avoid too much processed sugar. Go for sugar free drinks and no sugar in your tea coffee. Avoid sugary sweets in between meals. Also eat a balanced diet, not too much fat and not too many carbohydrates.

 

There is some (inconclusive) evidence that even artificially-sweetened drinks can be bad - for both weight gain and diabetes risk. This might just be because people who consume a lot of sweet drinks also consume too many calories elsewhere.

Posted

 

In general I do agree with you, Ophiolite, that lifestyle, diet, lack of exercise and obesity levels have greatest impact on Type 2 diabetes incidence rates, but there have been quite a few studies on genetical predisposition to getting it.

I acknowledged this by quoting iNow in post #10. ""There is a component of genetic predisposition, but much more relevant with type 2 diabetes are your diet and activity levels."

Posted

most of people with high blood pressure will get diabetes years later, do you guys notice that ?

it is not 100%, however the chance is very high. no idea what's the connection between them.

another thing i find is the blood sugar level in winter is usually higher.

Posted

Citation please.

no citation, it is what i observe, believe it or not.

scientific evidence always starts with what people observe.

Posted

Fresh - You're making a lot of assumptions. Any connection would be related to diet and activity levels. Bad choices on either increases incidence of diabetes and also blood pressure. As for your claim that blood sugar levels are higher in winter, if this does indeed occur, it again would likely be related to changes in diet and decrease in activity.

Posted

no citation, it is what i observe, believe it or not.

scientific evidence always starts with what people observe.

Yes, it begins with careful, controlled observation. You have not done this. If you have please provide the data that show you have considered the full range of variables that would be implicated.

 

What you have is an anecdote, that could be a useful spark for an investigation and the formation of a hypothesis, but the only thing that it is currently evidence of is that some people have diabetes and some have high blood pressure and some have both.

 

Guess what, all the people I know with high blood pressure do not have diabetes and all the people I know with diabetes have normal blood pressure. [sarcasm] So, obviously you much be wrong. [/sarcasm]

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