Has anyone prepared prednisolone in methyl cellulose?

[welikemice]

Hi all,

If anyone has had experience with preparing and dosing prednisolone, I would greatly appreciate your advice on a few things.

I am looking to prepare prednisolone in 0.5% methyl cellulose - preferably at a concentration of 2 mg/mL. Does anyone have experience using 0.5% MC as a vehicle for prednisolone? How is prednisolone’s stability in MC? Also, could you tell me how often you prepared the prednisolone solution for dosing?

Any information would be great.

Thanks!