CD4+ macrophages

[Dak]

why, oh why, do macrophages posess CD4 molecules, and why, oh why, do no immunological text books contain the reason that macrophages posess CD4 molecules?

 

i know that CD4 recognises MHC-II molecules, but i cant figure why macrophages would need to do this, unless its to prevent them from attempting to phagocytose other antigen-presenting cells (which would posess MHC-II)?

[Skye]

Looks like an active area of research.

 

http://upload.mcgill.ca/parasitology/esashietal.pdf