Thoughts on why chemotherapy is so ineffective in Brain Tumors.

[husmusen]

I was wondering why Brain tumors were so deadly.

Compared to other tissues, like bowel or skin, neurons are not

rapid dividers.

 

Which shoudl allow very tight targetting(and hence highr doses of)

the drugs which whack rapidly dividing cells with minimal colateral

damage.

 

Yet the figures suggest otherwise?

Any ideas why?

 

Cheers.

[Kylonicus]

Which is more important, your skin or your brain?

 

The brain is what makes you, you, and essentially, if it's severely damaged, your personality get's messed up.

 

I think the best treatment for brain tumors would be Valproic acid.

 

It has been shown to reduce and induce apptosis of cancer cells.

 

It's cheap and it's relatively tolerable, and well documented, being a common treatment for bipolar.

 

That's just my thought on the subject.

[Krul]

Brain tumors are so deadly because they often are not able to reach it with surgery and because chemotherapy in the brains is very dangerous.

[husmusen]

Why would chemotherapy be dangerous, the fact that neurons

divide at slower rates than most other tissues should

(I would have thought) made chemotherapy more targetable.

 

Cheers